4JR0
Human procaspase-3 bound to Ac-DEVD-CMK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Procaspase-3 | polymer | 247 | 28303.3 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1, Caspase-3 |
| 2 | C, D | Ac-DEVD-CMK | polymer | 6 | 537.0 | 2 | BIRD (PRD_000924) | ||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 423 | Chemie (HOH) |
Sequence modifications
A, B: 34 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ser 31 | - | expression tag |
| Asn 32 | - | expression tag |
| Ala 33 | - | expression tag |
| Ala 175 | Asp 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57680.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 57751.3 |
