4JPW
Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | HIV-1 CLADE A/E STRAIN 73TH057 GP120 WITH MUTATION H375S | polymer | 353 | 39160.4 | 1 | Pfam (PF00516) UniProt (by SIFTS) (Q0ED31) | HUMAN IMMUNODEFICIENCY VIRUS 1 | |
| 2 | B (H) | HEAVY CHAIN OF ANTIBODY 12A21 | polymer | 225 | 24411.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | LIGHT CHAIN OF ANTIBODY 12A21 | polymer | 210 | 22890.6 | 1 | Homo sapiens (human) | ||
| 4 | D, E, F, G, H... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 5 | N (G) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 6 | O, P, Q (G, H, L) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86462.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2450.4 | |
| All* | Total formula weight | 88912.8 |
