4JPA
Mmp13 in complex with a piperazine hydantoin ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Collagenase 3 | polymer | 173 | 19495.7 | 2 | UniProt (P45452) Pfam (PF00413) | Homo sapiens | Matrix metalloproteinase-13, MMP-13 |
| 2 | C, E, I, J (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | D, F, K, L (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G, M (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | H, N (A, B) | 3-[({2-[4-({[(4S)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl}sulfonyl)piperazin-1-yl]pyrimidin-5-yl}oxy)methyl]benzonitrile | non-polymer | 485.5 | 2 | Chemie (AZ6) | |||
| 6 | O, P (A, B) | water | water | 18.0 | 373 | Chemie (HOH) |
Sequence modifications
A, B: 103 - 274 (UniProt: P45452)
| PDB | External Database | Details |
|---|---|---|
| Met 102 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38991.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1439.0 | |
| All* | Total formula weight | 40430.3 |
