4JO8

Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	M157	polymer	269	30375.4	1	UniProt (Q6XK91) Pfam (PF11624)	Murid herpesvirus 1 (MuHV-1)
2	B (B)	Killer cell lectin-like receptor 8	polymer	157	18702.5	1	UniProt (Q60682) Pfam (PF08391) Pfam (PF00059)	Mus musculus (mouse)	Lymphocyte antigen 49h, Ly-49h, T-cell surface glycoprotein Ly-49H
3	C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 29 - 291 (UniProt: Q6XK91)

PDB	External Database	Details
Ala 29	Pro 29	engineered mutation
Gly 30	Asp 30	engineered mutation
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag

B: 107 - 263 (UniProt: Q60682)

PDB	External Database	Details
Met 107	Arg 107	engineered mutation
Gly 108	Pro 108	engineered mutation
Met 110	Tyr 110	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49077.9
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	49299.1

*Water molecules are not included.