4JMG

Crystal structure of the synthetic protein in complex with pY peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Clamp Ptpn11_pY580	polymer	203	22186.5	1		synthetic construct
2	B (B)	Tyrosine-protein phosphatase non-receptor type 11	polymer	13	1562.6	1	UniProt (Q06124)	Homo sapiens (human)	Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D, E (A, B)	water	water		18.0	145	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23749.2
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	23773.5

*Water molecules are not included.