4JKR
Crystal Structure of E. coli RNA Polymerase in complex with ppGpp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H (A, B, G, H) | DNA-directed RNA polymerase subunit alpha | polymer | 329 | 36558.7 | 4 | UniProt (K0BPQ3) | Escherichia coli | RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha |
| 2 | C, I (C, I) | DNA-directed RNA polymerase subunit beta | polymer | 1342 | 150820.9 | 2 | UniProt (C9QV90) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (A0A0E0Y7A2) | Escherichia coli | RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta |
| 3 | D, J (D, J) | DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' | polymer | 1416 | 156537.0 | 2 | UniProt (C5A0S8) | Escherichia coli | RNAP SUBUNIT BETA', RNA POLYMERASE SUBUNIT BETA', TRANSCRIPTASE SUBUNIT BETA' |
| 4 | E, K (E, K) | DNA-directed RNA polymerase subunit omega | polymer | 90 | 10118.4 | 2 | UniProt (C9QUL2) | Escherichia coli | RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega |
| 5 | F, L (F, L) | RNA polymerase sigma factor RpoD | polymer | 628 | 72206.3 | 2 | UniProt (P00579) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) Pfam (PF03979) Pfam (PF00140) | Escherichia coli | Sigma-70 |
| 6 | M, N, O, S, T... (A, C, D, E, F...) | STRONTIUM ION | non-polymer | 87.6 | 8 | Chemie (SR) | |||
| 7 | P, Z (D, K) | GUANOSINE-5',3'-TETRAPHOSPHATE | non-polymer | 603.2 | 2 | Chemie (G4P) | |||
| 8 | Q, R, W, X (D, J) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
D, J: 1 - 1407 (UniProt: C5A0S8)
F, L: 1 - 613 (UniProt: P00579)
| PDB | External Database | Details |
|---|---|---|
| Leu 1408 | - | expression tag |
| Glu 1409 | - | expression tag |
| Val 1410 | - | expression tag |
| His 1411 | - | expression tag |
| His 1412 | - | expression tag |
| His 1413 | - | expression tag |
| His 1414 | - | expression tag |
| His 1415 | - | expression tag |
| His 1416 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -14 | - | expression tag |
| Arg -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Ser -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 925599.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2168.9 | |
| All* | Total formula weight | 927768.7 |
