4JK2

X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, F, G	Escherichia coli RNA polymerase alpha subunit	polymer	329	36558.7	4	UniProt (P0A7Z4) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB	Escherichia coli	RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha
2	C, H	Escherichia coli RNA polymerase beta subunit	polymer	1342	150820.9	2	UniProt (P0A8V2) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) In PDB	Escherichia coli	RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta
3	D, I	Escherichia coli RNA polymerase beta' subunit	polymer	1407	155366.8	2	UniProt (P0A8T7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Escherichia coli	RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
4	E, J	Escherichia coli RNA polymerase omega subunit	polymer	91	10249.5	2	UniProt (H0QDQ9) Pfam (PF01192) UniProt (by SIFTS) (P0A800) In PDB	Escherichia coli	RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega
5	X, Y	Escherichia coli RNA polymerase sigma70 subunit	polymer	613	70352.2	2	UniProt (P00579) Pfam (PF03979) Pfam (PF00140) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) In PDB	Escherichia coli	Sigma-70
6	D, I	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
7	D	guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)	non-polymer		683.1	1	Chemie (0O2)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	919813.6
Non-Polymers*	Number of molecules	5
	Total formula weight	944.8
All*	Total formula weight	920758.4

*Water molecules are not included.