4JJD
Crystal structure of the N114A Abl-SH3 domain mutant at pH4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase ABL1 | polymer | 63 | 6966.7 | 1 | UniProt (P00519) Pfam (PF00018) | Homo sapiens (human) | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1, Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150 |
| 2 | B (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 3 | C, D (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E (A) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 60 - 121 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | expression tag |
| Ala 114 | Asn 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6966.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 152.1 | |
| All* | Total formula weight | 7118.8 |
