4JGD
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 390 | 42636.4 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (human) | DHOdehase, Dihydroorotate oxidase |
| 2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | A | UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 215.4 | 1 | Chemie (DET) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 6 | A | 1-[4-methyl-2-(naphthalen-2-ylamino)-1,3-thiazol-5-yl]ethanone | non-polymer | 282.4 | 1 | Chemie (4JG) | |||
| 7 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | expression tag |
| Gly 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Gly 21 | - | expression tag |
| His 22 | - | expression tag |
| Ile 23 | - | expression tag |
| Asp 24 | - | expression tag |
| Asp 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Asp 27 | - | expression tag |
| Lys 28 | - | expression tag |
| His 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42636.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1974.7 | |
| All* | Total formula weight | 44611.2 |
