4JEF
Crystal structure of human thymidylate synthase Y202A in inactive conformation.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Thymidylate synthase | polymer | 286 | 32925.8 | 1 | UniProt (P04818) Pfam (PF00303) In PDB | Homo sapiens (human) | TS, TSase |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 26 - 311 (UniProt: P04818)
| PDB | External Database | Details |
|---|---|---|
| Ala 202 | Tyr 202 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32925.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 33214.0 |
