4JE5

Crystal structure of the aromatic aminotransferase Aro8, a putative alpha-aminoadipate aminotransferase in Saccharomyces cerevisiae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Aromatic/aminoadipate aminotransferase 1	polymer	503	56567.0	3	UniProt (P53090) Pfam (PF00155)	Saccharomyces cerevisiae (Baker's yeast)	2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Aromatic amino acid aminotransferase 1, Aromatic amino acid aminotransferase I, Aromatic amino acid-requiring protein 8
2	D (D)	Aromatic/aminoadipate aminotransferase 1	polymer	503	56795.1	1	UniProt (P53090) Pfam (PF00155)	Saccharomyces cerevisiae (Baker's yeast)	2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Aromatic amino acid aminotransferase 1, Aromatic amino acid aminotransferase I, Aromatic amino acid-requiring protein 8
3	E (A)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	1	Chemie (PLP)
4	F, G, H, K, L (A, B, C)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	5	Chemie (EPE)
5	I, J (B, C)	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE	non-polymer		248.2	2	Chemie (PMP)
6	M, N, O, P (A, B, C, D)	water	water		18.0	1013	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 500 (UniProt: P53090)

PDB	External Database	Details
Gly -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

D: 1 - 500 (UniProt: P53090)

PDB	External Database	Details
Gly -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	226496.1
Non-Polymers*	Number of molecules	8
	Total formula weight	1935.0
All*	Total formula weight	228431.1

*Water molecules are not included.