4JDJ
Crystal structure of Serine/threonine-protein kinase PAK 4 F461V mutant in complex with Paktide T peptide substrate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase PAK 4 | polymer | 346 | 39155.1 | 1 | UniProt (O96013) Pfam (PF00069) In PDB | Homo sapiens (human) | p21-activated kinase 4, PAK-4 |
2 | B | Paktide T | polymer | 15 | 1816.1 | 1 | |||
3 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A: 286 - 591 (UniProt: O96013)
PDB | External Database | Details |
---|---|---|
Met 246 | - | expression tag |
Gly 247 | - | expression tag |
Ser 248 | - | expression tag |
Ser 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
His 252 | - | expression tag |
His 253 | - | expression tag |
His 254 | - | expression tag |
His 255 | - | expression tag |
Ser 256 | - | expression tag |
Ser 257 | - | expression tag |
Gly 258 | - | expression tag |
Leu 259 | - | expression tag |
Val 260 | - | expression tag |
Pro 261 | - | expression tag |
Arg 262 | - | expression tag |
Gly 263 | - | expression tag |
Ser 264 | - | expression tag |
His 265 | - | expression tag |
Met 266 | - | expression tag |
Glu 267 | - | expression tag |
Asn 268 | - | expression tag |
Leu 269 | - | expression tag |
Tyr 270 | - | expression tag |
Phe 271 | - | expression tag |
Gln 272 | - | expression tag |
Gly 273 | - | expression tag |
Ala 274 | - | expression tag |
Arg 275 | - | expression tag |
Ala 276 | - | expression tag |
Arg 277 | - | expression tag |
Gln 278 | - | expression tag |
Glu 279 | - | expression tag |
Asn 280 | - | expression tag |
Gly 281 | - | expression tag |
Met 282 | - | expression tag |
Pro 283 | - | expression tag |
Glu 284 | - | expression tag |
Lys 285 | - | expression tag |
Val 461 | Phe 461 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 40971.2 | |
All* | Total formula weight | 40971.2 |