4JDD
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1, Stratifin |
| 2 | B (B) | Estrogen receptor Peptide | polymer | 11 | 1158.1 | 1 | UniProt (P03372) | Homo sapiens | |
| 3 | C (A) | FUSICOCCIN | non-polymer | 680.8 | 1 | Chemie (FSC) PubChem (46936214) PubChem (24124005) PubChem (44201245) PubChem (52940549) PubChem (57061783) PubChem (58892803) PubChem (143471529) PubChem (89167108) PubChem (89358776) PubChem (270757) PubChem (71308204) PubChem (447573) PubChem (89352860) PubChem (89424149) PubChem (91305733) PubChem (5381214) PubChem (124914704) PubChem (124914702) PubChem (125183286) PubChem (6437071) PubChem (134693211) PubChem (12309993) PubChem (138107212) PubChem (11534864) PubChem (124914703) PubChem (124914705) PubChem (146157920) PubChem (163008024) PubChem (134688043) PubChem (163008025) PubChem (163728719) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27701.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 680.8 | |
| All* | Total formula weight | 28381.8 |
