4JDD
14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1, Stratifin |
| 2 | B | Estrogen receptor Peptide | polymer | 11 | 1158.1 | 1 | UniProt (P03372) In PDB | Homo sapiens | |
| 3 | A | FUSICOCCIN | non-polymer | 680.8 | 1 | Chemie (FSC) | |||
| 4 | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | EXPRESSION TAG |
| Ala -3 | - | EXPRESSION TAG |
| Met -2 | - | EXPRESSION TAG |
| Gly -1 | - | EXPRESSION TAG |
| Ser 0 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27701.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 680.8 | |
| All* | Total formula weight | 28381.8 |
