4JBH

2.2A resolution structure of cobalt and zinc bound thermostable alcohol dehydrogenase from Pyrobaculum aerophilum

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Alcohol dehydrogenase (Zinc)	polymer	370	38688.3	4	UniProt (Q8ZUP0) Pfam (PF08240) Pfam (PF00107)	Pyrobaculum aerophilum
2	E, H, K, N (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	F, I, L, O (A, B, C, D)	COBALT (II) ION	non-polymer		58.9	4	Chemie (CO)
4	G, J, M (B, C, D)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
5	P, Q, R, S (A, B, C, D)	water	water		18.0	309	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 331 (UniProt: Q8ZUP0)

PDB	External Database	Details
Met -38	-	expression tag
Gly -37	-	expression tag
Ser -36	-	expression tag
Ser -35	-	expression tag
His -34	-	expression tag
His -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
Ser -28	-	expression tag
Ser -27	-	expression tag
Gly -26	-	expression tag
Leu -25	-	expression tag
Val -24	-	expression tag
Pro -23	-	expression tag
Arg -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
Met -18	-	expression tag
Ala -17	-	expression tag
Ser -16	-	expression tag
Met -15	-	expression tag
Thr -14	-	expression tag
Gly -13	-	expression tag
Gly -12	-	expression tag
Gln -11	-	expression tag
Gln -10	-	expression tag
Met -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
His -1	-	expression tag
Glu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154753.2
Non-Polymers*	Number of molecules	11
	Total formula weight	603.7
All*	Total formula weight	155356.9

*Water molecules are not included.