4JAU
Structural basis of a rationally rewired protein-protein interface (HK853mutant A268V, A271G, T275M, V294T and D297E)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histidine kinase | polymer | 258 | 29438.4 | 1 | UniProt (Q9WZV7) Pfam (PF00512) Pfam (PF02518) | Thermotoga maritima | Sensor histidine kinase |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C (A) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 232 - 489 (UniProt: Q9WZV7)
| PDB | External Database | Details |
|---|---|---|
| Val 268 | Ala 268 | engineered mutation |
| Gly 271 | Ala 271 | engineered mutation |
| Met 275 | Thr 275 | engineered mutation |
| Thr 294 | Val 294 | engineered mutation |
| Glu 297 | Asp 297 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29438.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 427.2 | |
| All* | Total formula weight | 29865.6 |
