4J9J

Structure of designed HisF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Imidazole glycerol phosphate synthase subunit HisF	polymer	246	26326.3	1	UniProt (Q9X0C6) Pfam (PF00977)	Thermotoga maritima	IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF
2	B (A)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A: 1 - 120 (UniProt: Q9X0C6)

PDB	External Database	Details
Leu 0	-	expression tag
Ile 5	Ser 101	engineered mutation
Ala 44	Val 140	engineered mutation
Ala 75	Thr 171	engineered mutation
Gly 80	Asp 176	engineered mutation

A: 121 - 245 (UniProt: Q9X0C6)

PDB	External Database	Details
Val 155	Asp 130	engineered mutation
Val 201	Asp 176	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26326.3
All*	Total formula weight	26326.3

*Water molecules are not included.