4J9H
Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Tyrosine-protein kinase ABL1 | polymer | 63 | 7009.7 | 6 | UniProt (P00519) Pfam (PF00018) | Homo sapiens (human) | Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150 |
| 2 | G, H, I, J, K... (G, H, I, J, K...) | P7 | polymer | 11 | 1059.2 | 6 | |||
| 3 | M (E) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 60 - 121 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 48413.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 48509.5 |
