4J9G
Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Tyrosine-protein kinase ABL1 | polymer | 63 | 7009.7 | 3 | UniProt (P00519) Pfam (PF00018) | Homo sapiens (human) | Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150 |
| 2 | B, D, F (B, D, F) | P7 | polymer | 11 | 1059.2 | 3 | |||
| 3 | G (E) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | H (E) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, C, E: 60 - 121 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 24206.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 188.2 | |
| All* | Total formula weight | 24394.9 |
