4J9B
Crystal structure of the Abl-SH3 domain H59Q-N96T mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase ABL1 | polymer | 63 | 6986.7 | 1 | UniProt (P00519) Pfam (PF00018) In PDB | Homo sapiens (human) | Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150 |
2 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
3 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 60 - 121 (UniProt: P00519)
PDB | External Database | Details |
---|---|---|
Met 59 | - | initiating methionine |
Gln 95 | His 95 | engineered mutation |
Thr 96 | Asn 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 6986.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 212.2 | |
All* | Total formula weight | 7198.9 |