4J8O
SET7/9 in complex with TAF10K189A peptide and AdoHcy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETD7 | polymer | 261 | 29043.3 | 1 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) | Homo sapiens (human) | Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7/9 |
| 2 | B (B) | Transcription initiation factor TFIID subunit 10 | polymer | 11 | 1197.4 | 1 | UniProt (Q12962) | Homo sapiens | STAF28, Transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, TAFII30 |
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
B: 186 - 195 (UniProt: Q12962)
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | expression tag |
| Ala 107 | - | expression tag |
| Met 108 | - | expression tag |
| Gly 109 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 185 | - | expression tag |
| Ala 189 | Lys 189 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30240.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 30625.1 |
