4J83
SET7/9 in complex with TAF10K189A peptide and AdoMet
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETD7 | polymer | 261 | 29043.3 | 1 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) | Homo sapiens (human) | Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7/9 |
| 2 | B (B) | Transcription initiation factor TFIID subunit 10 | polymer | 11 | 1197.4 | 1 | UniProt (Q12962) | Homo sapiens | STAF28, Transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, TAFII30 |
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (58766358) PubChem (73897310) PubChem (9865603) PubChem (87224684) PubChem (12312798) PubChem (131697735) PubChem (145712080) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
B: 186 - 195 (UniProt: Q12962)
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | expression tag |
| Ala 107 | - | expression tag |
| Met 108 | - | expression tag |
| Gly 109 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 185 | - | expression tag |
| Ala 189 | Lys 189 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30240.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 398.4 | |
| All* | Total formula weight | 30639.1 |
