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4J83

SET7/9 in complex with TAF10K189A peptide and AdoMet

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHistone-lysine N-methyltransferase SETD7polymer26129043.31UniProt (Q8WTS6)
Pfam (PF22648)
Pfam (PF00856)
In PDB
Homo sapiens (human)Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7/9
2BTranscription initiation factor TFIID subunit 10polymer111197.41UniProt (Q12962)
In PDB
Homo sapiensSTAF28, Transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, TAFII30
3AS-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
4waterwater18.0147Chemie (HOH)
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
PDBExternal DatabaseDetails
Gly 106-expression tag
Ala 107-expression tag
Met 108-expression tag
Gly 109-expression tag
B: 186 - 195 (UniProt: Q12962)
PDBExternal DatabaseDetails
Ace 185-expression tag
Ala 189Lys 189engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight30240.7
Non-Polymers*Number of molecules1
Total formula weight398.4
All*Total formula weight30639.1
*Water molecules are not included.

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PDB entries from 2024-08-28

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