4J7Y
Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukotriene C4 synthase | polymer | 156 | 17411.5 | 1 | UniProt (Q16873) Pfam (PF01124) | Homo sapiens (human) | LTC4 synthase, Leukotriene-C(4) synthase |
| 2 | B (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide | non-polymer | 453.5 | 1 | Chemie (1JP) |
Sequence modifications
A: 2 - 150 (UniProt: Q16873)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17411.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 608.3 | |
| All* | Total formula weight | 18019.8 |
