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4J6R

Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1GEnvelope glycoprotein gp160polymer35939980.11Pfam (PF00516)
UniProt (by SIFTS) (Q8J581)
In PDB
HUMAN IMMUNODEFICIENCY VIRUS 1
2HHEAVY CHAIN OF ANTIBODY VRC23polymer22424445.51Homo sapiens
3LLIGHT CHAIN OF ANTIBODY VRC23polymer21022846.41Homo sapiens
4G2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.29Chemie (NAG)
5L, GCALCIUM IONnon-polymer40.12Chemie (CA)
6L, G, H1,2-ETHANEDIOLnon-polymer62.115Chemie (EDO)
7H(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
8H2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
9L(R,R)-2,3-BUTANEDIOLnon-polymer90.11Chemie (BU3)
10waterwater18.01020Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87272.0
Non-Polymers*Number of molecules29
Total formula weight3332.5
All*Total formula weight90604.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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