4J3B
A naturally variable residue in the S1 subsite of M1-family aminopeptidases modulates catalytic properties and promotes functional specialization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M1 family aminopeptidase | polymer | 889 | 103602.5 | 1 | UniProt (O96935) Pfam (PF17900) Pfam (PF01433) Pfam (PF11940) Pfam (PF17432) | Plasmodium falciparum | Pfa-M1 |
| 2 | B (A) | ARGININE | non-polymer | 175.2 | 1 | Chemie (ARG) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | water | water | 18.0 | 438 | Chemie (HOH) |
Sequence modifications
A: 197 - 1085 (UniProt: O96935)
| PDB | External Database | Details |
|---|---|---|
| Pro 459 | Val 459 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 103602.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 264.9 | |
| All* | Total formula weight | 103867.4 |
