4J2M
Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphotriesterase, putative | polymer | 323 | 34688.1 | 1 | UniProt (Q9RVU2) Pfam (PF02126) | Deinococcus radiodurans | |
| 2 | B, C (A) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | D (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 1 - 323 (UniProt: Q9RVU2)
| PDB | External Database | Details |
|---|---|---|
| Leu 28 | Tyr 28 | engineered mutation |
| Asn 71 | Asp 71 | engineered mutation |
| Phe 97 | Tyr 97 | engineered mutation |
| Gly 101 | Glu 101 | engineered mutation |
| Asp 179 | Glu 179 | engineered mutation |
| Leu 235 | Val 235 | engineered mutation |
| Met 270 | Leu 270 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34688.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 117.9 | |
| All* | Total formula weight | 34806.0 |
