4J22

Tankyrase 2 in complex with 3-chloro-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tankyrase-2	polymer	210	23993.2	2	UniProt (Q9H2K2) Pfam (PF00644)	Homo sapiens (human)	TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein
2	C, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, E, H, I (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	F, J (A, B)	3-chloro-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide	non-polymer		425.9	2	Chemie (AJ7)
5	K, L (A, B)	water	water		18.0	256	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47986.4
Non-Polymers*	Number of molecules	8
	Total formula weight	1366.9
All*	Total formula weight	49353.3

*Water molecules are not included.