4IZ6

Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Enterobactin synthase component E, Isochorismatase	polymer	635	70408.6	2	UniProt (P10378) UniProt (P0ADI4) Pfam (PF00501) Pfam (PF13193) Pfam (PF00550) In PDB	Escherichia coli	Enterochelin synthase E, 2,3-dihydroxybenzoate-AMP ligase, Dihydroxybenzoic acid-activating enzyme, S-dihydroxybenzoyltransferase, 3 dihydro-2, 3 dihydroxybenzoate synthase, Enterobactin synthase component B, Enterochelin synthase B, Isochorismate lyase
2	A, B	5'-deoxy-5'-({[2-(2,3-dihydroxyphenyl)ethyl]sulfonyl}amino)adenosine	non-polymer		466.5	2	Chemie (1HZ)
3	A, B	4'-PHOSPHOPANTETHEINE	non-polymer		358.3	2	Chemie (PNS)
4		water	water		18.0	205	Chemie (HOH)

Sequence modifications

A, B: 1 - 536 (UniProt: P10378)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag
Gly 537	-	linker
Arg 538	-	linker
Ala 539	-	linker
Ser 540	-	linker

A, B: 541 - 615 (UniProt: P0ADI4)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	140817.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1649.6
All*	Total formula weight	142466.9

*Water molecules are not included.