4IZ0
Crystal structure of HCV NS5B polymerase in complex with 2,4,5-trichloro-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | RNA-directed RNA polymerase | polymer | 576 | 64285.6 | 2 | UniProt (O92972) Pfam (PF00998) In PDB | Hepatitis C virus (HCV) | NS5B, p68 |
2 | A | 2,4,5-trichloro-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide | non-polymer | 341.6 | 2 | Chemie (2BI) | |||
3 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 570 (UniProt: O92972)
PDB | External Database | Details |
---|---|---|
His 571 | - | expression tag |
His 572 | - | expression tag |
His 573 | - | expression tag |
His 574 | - | expression tag |
His 575 | - | expression tag |
His 576 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128571.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 683.2 | |
All* | Total formula weight | 129254.5 |