4IYP

structure of the nPP2Ac-alpha4 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Immunoglobulin-binding protein 1	polymer	222	25926.4	1	UniProt (P78318) Pfam (PF04177) In PDB	Homo sapiens (human)	B-cell signal transduction molecule alpha 4, Protein alpha-4, CD79a-binding protein 1, Protein phosphatase 2/4/6 regulatory subunit, Renal carcinoma antigen NY-REN-16
2	C	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	polymer	151	17896.8	1	UniProt (P67775) Pfam (PF00149) In PDB	Homo sapiens (human)	PP2A-alpha, Replication protein C, RP-C
3		water	water		18.0	34	Chemie (HOH)

Sequence modifications

A: 2 - 234 (UniProt: P78318)

PDB	External Database	Details
Gly -1	-	EXPRESSION TAG
Ser 0	-	EXPRESSION TAG
Mse 1	-	EXPRESSION TAG
-	Lys 128	DELETION
-	Thr 129	DELETION
-	Met 130	DELETION
-	Asn 131	DELETION
-	Asn 132	DELETION
-	Ser 133	DELETION
-	Ala 134	DELETION
-	Glu 135	DELETION
-	Asn 136	DELETION
-	His 137	DELETION
-	Thr 138	DELETION
-	Ala 139	DELETION
-	Asn 140	DELETION
-	Ser 141	DELETION

C: 6 - 153 (UniProt: P67775)

PDB	External Database	Details
Gly 3	-	EXPRESSION TAG
Ser 4	-	EXPRESSION TAG
Mse 5	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43823.2
All*	Total formula weight	43823.2

*Water molecules are not included.