4IXU
Crystal structure of human Arginase-2 complexed with inhibitor 11d: {(5R)-5-amino-5-carboxy-5-[(3-endo)-8-(3,4-dichlorobenzyl)-8-azabicyclo[3.2.1]oct-3-yl]pentyl}(trihydroxy)borate(1-)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Arginase-2, mitochondrial | polymer | 306 | 33231.7 | 3 | UniProt (P78540) Pfam (PF00491) In PDB | Homo sapiens (human) | Kidney-type arginase, Non-hepatic arginase, Type II arginase |
| 2 | A, B, C | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 3 | A, B, C | BENZAMIDINE | non-polymer | 120.2 | 3 | Chemie (BEN) | |||
| 4 | A, B, C | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 6 | Chemie (BME) | |||
| 5 | A, B, C | {(5R)-5-amino-5-carboxy-5-[(3-endo)-8-(3,4-dichlorobenzyl)-8-azabicyclo[3.2.1]oct-3-yl]pentyl}(trihydroxy)borate(1-) | non-polymer | 460.2 | 3 | Chemie (38I) | |||
| 6 | water | water | 18.0 | 798 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99695.0 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2539.4 | |
| All* | Total formula weight | 102234.4 |
