4IVQ

Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with IN43/5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thymidine kinase	polymer	331	35779.1	2	UniProt (P03176) Pfam (PF00693) UniProt (by SIFTS) (P0DTH5)	Human herpesvirus 1 (HHV-1)	HSV1-TK
2	C, F (A, B)	6-[3-hydroxy-2-(hydroxymethyl)prop-1-en-1-yl]-4-methoxy-1,5-dimethylpyrimidin-2(1H)-one	non-polymer		240.3	2	Chemie (I43)
3	D, E, G (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	H, I (A, B)	water	water		18.0	203	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71558.2
Non-Polymers*	Number of molecules	5
	Total formula weight	768.7
All*	Total formula weight	72326.9

*Water molecules are not included.