4IVP

Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with IN51/20

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Thymidine kinase	polymer	331	35779.1	2	UniProt (P03176) Pfam (PF00693) UniProt (by SIFTS) (P0DTH5) In PDB	Human herpesvirus 1 (HHV-1)	HSV1-TK
2	A, B	6-[3-hydroxy-2-(hydroxymethyl)prop-1-en-1-yl]-5-methylpyrimidine-2,4(1H,3H)-dione	non-polymer		212.2	2	Chemie (I51)
3	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4		water	water		18.0	218	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71558.2
Non-Polymers*	Number of molecules	6
	Total formula weight	808.7
All*	Total formula weight	72366.8

*Water molecules are not included.