4IV8

Crystal structure of N-methyl transferase from Plasmodium knowlesi complexed with S-adenosyl methionine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphoethanolamine N-methyltransferase,putative	polymer	284	33187.9	2	UniProt (B3L8G9) Pfam (PF13649) UniProt (by SIFTS) (A0A384KJX3)	Plasmodium knowlesi
2	C, E (A, B)	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
3	D, F (A, B)	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
4	G, H (A, B)	water	water		18.0	363	Chemie (HOH)

Sequence modifications

A, B: 2 - 265 (UniProt: B3L8G9)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66375.8
Non-Polymers*	Number of molecules	4
	Total formula weight	953.1
All*	Total formula weight	67329.0

*Water molecules are not included.