4IV0

Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine and phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphoethanolamine N-methyltransferase, putative	polymer	284	33096.0	2	UniProt (A5K867) Pfam (PF13649)	Plasmodium vivax
2	C, E (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3	D, F (A, B)	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
4	G (B)	BETA-MERCAPTOETHANOL	non-polymer		78.1	1	Chemie (BME)
5	H (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	I, J (A, B)	water	water		18.0	992	Chemie (HOH)

Sequence modifications

A, B: 1 - 264 (UniProt: A5K867)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66192.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1127.0
All*	Total formula weight	67319.0

*Water molecules are not included.