4IU6
Human Methionine Aminopeptidase in complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methionine aminopeptidase 1 | polymer | 384 | 42999.9 | 1 | UniProt (P53582) Pfam (PF15801) Pfam (PF00557) In PDB | Homo sapiens (human) | MAP 1, MetAP 1, Peptidase M 1 |
2 | A | COBALT (II) ION | non-polymer | 58.9 | 3 | Chemie (CO) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
4 | A | 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline | non-polymer | 397.5 | 1 | Chemie (FZ1) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
6 | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42999.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 805.5 | |
All* | Total formula weight | 43805.4 |