4ITD

Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA (5'-D(*CP*GP*CP*GP*(C6G)P*AP*TP*TP*CP*GP*CP*G)-3')	polymer	12	3737.4	2
2	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	D (A)	2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE	non-polymer		424.5	1	Chemie (HT)
4	E, F (A, B)	water	water		18.0	80	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	7474.9
Non-Polymers*	Number of molecules	2
	Total formula weight	448.8
All*	Total formula weight	7923.7

*Water molecules are not included.