4ISQ
Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Neurotoxin | polymer | 431 | 50065.4 | 3 | UniProt (Q9LBR1) Pfam (PF07953) Pfam (PF07951) | Clostridium botulinum | |
| 2 | D, E, F (D, E, F) | Synaptotagmin-1 | polymer | 21 | 2471.8 | 3 | UniProt (P21579) | Homo sapiens | Synaptotagmin I, SytI, p65 |
| 3 | AA, BA, CA, DA, EA... (C, A, B) | SULFATE ION | non-polymer | 96.1 | 20 | Chemie (SO4) | |||
| 4 | FA, GA, HA, M, N... (C, A, B) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | IA, JA, KA (A, B, C) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B, C: 863 - 1284 (UniProt: Q9LBR1)
| PDB | External Database | Details |
|---|---|---|
| Met 854 | - | expression tag |
| His 855 | - | expression tag |
| His 856 | - | expression tag |
| His 857 | - | expression tag |
| His 858 | - | expression tag |
| His 859 | - | expression tag |
| His 860 | - | expression tag |
| Tyr 861 | - | expression tag |
| Phe 862 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 157611.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2658.0 | |
| All* | Total formula weight | 160269.6 |
