4IRV
Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cytotoxicity-associated immunodominant antigen | polymer | 221 | 25480.0 | 4 | UniProt (P55980) | Helicobacter pylori | 120 kDa protein, CAG pathogenicity island protein 26 |
| 2 | E, F, G, H (E, F, G, H) | Apoptosis-stimulating of p53 protein 2 | polymer | 62 | 6609.3 | 4 | UniProt (Q13625) | Homo sapiens (human) | Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2 |
| 3 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 513 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 19 - 235 (UniProt: P55980)
E, F, G, H: 726 - 782 (UniProt: Q13625)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Val 17 | - | expression tag |
| Asp 18 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 721 | - | expression tag |
| Pro 722 | - | expression tag |
| Lys 723 | - | expression tag |
| Leu 724 | - | expression tag |
| Ala 725 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 128357.3 | |
| All* | Total formula weight | 128357.3 |
