4IRL
X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Maltose-binding periplasmic protein, Novel protein similar to vertebrate guanylate binding protein family | polymer | 476 | 52318.1 | 3 | UniProt (P0AEX9) UniProt (B0V1H4) Pfam (PF01547) Pfam (PF00619) | Escherichia coli (leopard danio zebra danio zebra fish) | MBP, MMBP, Maltodextrin-binding protein, Uncharacterized protein |
| 2 | D, E, F (D, E, F) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 666.6 | 3 | In PDB BIRD (PRD_900010) GlyTouCan (G87171PZ) | alpha-maltotetraose | ||
| 3 | G, K, R (A, B, C) | MALONATE ION | non-polymer | 102.0 | 3 | Chemie (MLI) | |||
| 4 | H, L, M, N, S (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | I, O, U (A, B, C) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | J, P, Q, V (A, B, C) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 7 | T (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | W, X, Y (A, B, C) | water | water | 18.0 | 1922 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 359 (UniProt: P0AEX9)
A, B, C: 376 - 468 (UniProt: B0V1H4)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Ala 83 | Asp 108 | conflict |
| Ala 84 | Lys 109 | conflict |
| Ala 173 | Glu 198 | conflict |
| Ala 174 | Asn 199 | conflict |
| Ala 240 | Lys 265 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 360 | - | linker |
| Ala 361 | - | linker |
| Leu 362 | - | linker |
| Ala 363 | - | linker |
| Ala 364 | - | linker |
| Ala 365 | - | linker |
| Gln 366 | - | linker |
| Thr 367 | - | linker |
| Asn 368 | - | linker |
| Ala 369 | - | linker |
| Ala 370 | - | linker |
| Arg 371 | - | linker |
| Ala 372 | - | linker |
| Ala 373 | - | linker |
| Ala 374 | - | linker |
| Ala 375 | - | linker |
| Ser 412 | Asn 909 | conflict |
| Tyr 416 | Asn 913 | conflict |
| Leu 469 | - | expression tag |
| Glu 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 156954.3 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1999.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 991.7 | |
| All* | Total formula weight | 159945.8 |
