4IQ2
P21 crystal form of FKBP12.6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase FKBP1B | polymer | 107 | 11673.3 | 2 | UniProt (P68106) Pfam (PF00254) | Homo sapiens (human) | PPIase FKBP1B, 12.6 kDa FK506-binding protein, 12.6 kDa FKBP, FKBP-12.6, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP12.6, Rotamase, h-FKBP-12 |
| 2 | C (A) | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 107 (UniProt: P68106)
| PDB | External Database | Details |
|---|---|---|
| Val 22 | Cys 23 | engineered mutation |
| Ile 76 | Cys 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23346.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 104.1 | |
| All* | Total formula weight | 23450.7 |
