4IPJ
Crystal Structure of R314K N-acetyl Neuraminic Acid Synthase from Neiserria meningitidis with Malate bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polysialic acid capsule biosynthesis protein SiaC | polymer | 351 | 38495.8 | 1 | UniProt (Q7DDU0) Pfam (PF03102) Pfam (PF08666) UniProt (by SIFTS) (Q57265) | Neisseria meningitidis | N-Acetyl Neuraminic Acid Synthase |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | (2S)-2-hydroxybutanedioic acid | non-polymer | 134.1 | 1 | Chemie (LMR) | |||
| 4 | D (A) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: Q7DDU0)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Lys 314 | Arg 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38495.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.0 | |
| All* | Total formula weight | 38684.9 |
