4IOP

Crystal structure of NKp65 bound to its ligand KACL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	C-type lectin domain family 2 member A	polymer	142	16239.2	1	UniProt (Q6UVW9) Pfam (PF00059) In PDB	Homo sapiens (human)	Keratinocyte-associated C-type lectin, KACL, Proliferation-induced lymphocyte-associated receptor, PILAR
2	B	Killer cell lectin-like receptor subfamily F member 2	polymer	158	17968.0	1	UniProt (D3W0D1) Pfam (PF00059) In PDB	Homo sapiens (human)	Lectin-like receptor F2, Activating coreceptor NKp65
3	C, D	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G62182OO)

Sequence modifications

A: 46 - 174 (UniProt: Q6UVW9)

PDB	External Database	Details
Asp 42	-	expression tag
Leu 43	-	expression tag
Gly 44	-	expression tag
Ser 45	-	expression tag
Ala 175	-	expression tag
Ala 176	-	expression tag
Ala 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag

B: 63 - 207 (UniProt: D3W0D1)

PDB	External Database	Details
Asp 59	-	expression tag
Leu 60	-	expression tag
Gly 61	-	expression tag
Ser 62	-	expression tag
Ala 208	-	expression tag
Ala 209	-	expression tag
Ala 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34207.2
Branched	Number of molecules	2
	Total formula weight	1173.1
All*	Total formula weight	35380.3

*Water molecules are not included.