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4IH6

Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BRNA-directed RNA polymerasepolymer57063354.72UniProt (P26663)
Pfam (PF00998)
In PDB
Hepatitis C virus (HCV)NS5B, p68
2A, B(5S)-3-(4-tert-butylbenzyl)-5-(propan-2-yl)imidazolidine-2,4-dionenon-polymer288.42Chemie (1EP)
3waterwater18.0589Chemie (HOH)
Sequence modifications
A, B: 2 - 570 (UniProt: P26663)
PDBExternal DatabaseDetails
His 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight126709.4
Non-Polymers*Number of molecules2
Total formula weight576.8
All*Total formula weight127286.2
*Water molecules are not included.

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PDB entries from 2024-07-24

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