4IH5
Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA-directed RNA polymerase | polymer | 570 | 63354.7 | 2 | UniProt (P26663) Pfam (PF00998) | Hepatitis C virus (HCV) | NS5B, p68 |
| 2 | C, D (A, B) | 4-(2-phenylhydrazinyl)-1H-pyrazolo[3,4-d]pyrimidine | non-polymer | 226.2 | 2 | Chemie (12R) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 1085 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 570 (UniProt: P26663)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126709.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 452.5 | |
| All* | Total formula weight | 127161.9 |
