4IGT
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist ZA302 at 1.24A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor 2 | polymer | 263 | 29221.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (rat) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | B (A) | (4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acid | non-polymer | 248.2 | 1 | Chemie (3ZA) | |||
| 3 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 5 | G, H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | K (A) | water | water | 18.0 | 340 | Chemie (HOH) |
Sequence modifications
A: 413 - 527 (UniProt: P19491)
A: 653 - 796 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 411 | - | expression tag |
| Ala 412 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 651 | - | linker |
| Thr 652 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29221.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 911.7 | |
| All* | Total formula weight | 30133.4 |
