4IFC

Crystal Structure of ADP-bound Human PRPF4B kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Serine/threonine-protein kinase PRP4 homolog	polymer	358	41933.5	2	UniProt (Q13523) Pfam (PF00069) In PDB	Homo sapiens (human)	PRP4 kinase, PRP4 pre-mRNA-processing factor 4 homolog
2	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4		water	water		18.0	333	Chemie (HOH)

Sequence modifications

A, B: 657 - 1007 (UniProt: Q13523)

PDB	External Database	Details
Met 656	-	EXPRESSION TAG
His 1008	-	EXPRESSION TAG
His 1009	-	EXPRESSION TAG
His 1010	-	EXPRESSION TAG
His 1011	-	EXPRESSION TAG
His 1012	-	EXPRESSION TAG
His 1013	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83866.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1142.6
All*	Total formula weight	85009.5

*Water molecules are not included.