4IC2
Crystal structure of the XIAP RING domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase XIAP | polymer | 74 | 8395.0 | 2 | UniProt (P98170) Pfam (PF13920) | Homo sapiens (human) | Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP |
| 2 | C, D, E, F (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | G (B) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A, B: 429 - 497 (UniProt: P98170)
| PDB | External Database | Details |
|---|---|---|
| Gly 424 | - | expression tag |
| Pro 425 | - | expression tag |
| Leu 426 | - | expression tag |
| Gly 427 | - | expression tag |
| Ser 428 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16790.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 320.3 | |
| All* | Total formula weight | 17110.3 |
