4IC0
Crystal Structure of PAI-1 in Complex with Gallate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Plasminogen activator inhibitor 1 | polymer | 379 | 42795.1 | 4 | UniProt (P05121) Pfam (PF00079) In PDB | Homo sapiens (human) | PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1 |
2 | A, C | 3,4,5-trihydroxybenzoic acid | non-polymer | 170.1 | 2 | Chemie (GDE) |
Sequence modifications
A, B, C, D: 1 - 379 (UniProt: P05121)
PDB | External Database | Details |
---|---|---|
His 150 | Asn 173 | engineered mutation |
Thr 154 | Lys 177 | engineered mutation |
Gln 158 | Asp 181 | engineered mutation |
Leu 319 | Gln 342 | engineered mutation |
Ile 354 | Met 377 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 171180.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 340.2 | |
All* | Total formula weight | 171520.5 |