4IBR
Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S/E104K mutations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TEM-94 ES-beta-lactamase | polymer | 263 | 28800.9 | 1 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) In PDB | Escherichia coli | |
| 2 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 4 | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A: 25 - 287 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | Ala 40 | engineered mutation |
| Ala 51 | Asn 50 | engineered mutation |
| Lys 103 | Glu 102 | engineered mutation |
| Gly 119 | Arg 118 | engineered mutation |
| Thr 181 | Met 180 | engineered mutation |
| Val 183 | Ala 182 | conflict |
| Ala 200 | Leu 199 | engineered mutation |
| Ser 237 | Gly 236 | engineered mutation |
| Met 262 | Thr 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28800.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 235.3 | |
| All* | Total formula weight | 29036.2 |
