4IBK
Ebola virus VP35 bound to small molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polymerase cofactor VP35 | polymer | 129 | 14210.5 | 2 | UniProt (Q05127) Pfam (PF02097) | Ebola virus (ZEBOV) | |
| 2 | C, G (A, B) | 3-{(2S)-2-(7-chloro-1,3-benzodioxol-5-yl)-3-[(5-chlorothiophen-2-yl)carbonyl]-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl}benzoic acid | non-polymer | 518.3 | 2 | Chemie (1DE) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence modifications
A, B: 215 - 340 (UniProt: Q05127)
| PDB | External Database | Details |
|---|---|---|
| Gly 212 | - | expression tag |
| His 213 | - | expression tag |
| Met 214 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28421.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1285.0 | |
| All* | Total formula weight | 29706.1 |
